Evaluation of the Effectiveness of a Feline Toxoplasma Vaccine in Reducing the Exposure of Swine to Toxoplasma Gondii
Mateus-Pinilla, Nohra Esperanza
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https://hdl.handle.net/2142/87646
Description
Title
Evaluation of the Effectiveness of a Feline Toxoplasma Vaccine in Reducing the Exposure of Swine to Toxoplasma Gondii
Author(s)
Mateus-Pinilla, Nohra Esperanza
Issue Date
2000
Doctoral Committee Chair(s)
Weigel, Ronald M.
Department of Study
Veterinary Pathobiology
Discipline
Veterinary Pathobiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Agriculture, Animal Pathology
Language
eng
Abstract
The second study used a deterministic dynamic computer simulation model of the transmission of T. gondii in the swine farm ecosystem in a factorial experimental design to test the following hypotheses. T. gondii infection in finishing pigs decreases with (1) vaccination of susceptible cats, (2) increased cat capture rate (for vaccination), (3) decreased number of cats, (4) decreased T. gondii prevalence in cats, and (5) decreased oocyst survival time. Simulations were run for 10 years, with a weekly interval. Elimination of T. gondii in finishing pigs increased with a decrease in oocysts survival and a decrease in the number of cats in the farm. T. gondii prevalence in finishing pigs decreased with a decrease in the number of cats, a decrease in oocyst survival time, vaccinating and using an optimized vaccination schedule. Initial T. gondii prevalence in cats had no effect on outcome. Vaccination had less impact in decreasing T. gondii infection in finishing pigs than a decrease in the number of farm cats.
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