University of Illinois Urbana-Champaign

An Interactive Natural Host Model System for a Swine Alphaherpesvirus: Aujeszky's Disease Virus Cell Interactions in Immortalized Porcine Olfactory Neuroblasts

Uebing, Astrid Ulrike

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https://hdl.handle.net/2142/87637

Description

Title
An Interactive Natural Host Model System for a Swine Alphaherpesvirus: Aujeszky's Disease Virus Cell Interactions in Immortalized Porcine Olfactory Neuroblasts
Author(s)
Uebing, Astrid Ulrike
Issue Date
2007
Doctoral Committee Chair(s)
Gail Scherba
Department of Study
Veterinary Pathobiology
Discipline
Veterinary Pathobiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Virology
Language
eng
Abstract
Following the comprehensive characterization of the novel cell line, we infected the OBGF400 cells with ADY and investigated the ensuing comprehensive gene expression profile in comparison to a non-neuronal cell line, again by utilizing the Affymetrix array chip. The conducted studies exerted a highly cell-specific transcriptional response with neuron-specific attributes in the swine neuronal cell line.
Graduation Semester
2007
Type of Resource
text
Permalink
http://hdl.handle.net/2142/87637

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