Magnetic Resonance Imaging (Mri) Studies of the Rat Olfactory System
Agahi, Saied
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https://hdl.handle.net/2142/87262
Description
Title
Magnetic Resonance Imaging (Mri) Studies of the Rat Olfactory System
Author(s)
Agahi, Saied
Issue Date
1997
Doctoral Committee Chair(s)
Esmail Meisami
Department of Study
Molecular and Integrative Physiology
Discipline
Molecular and Integrative Physiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biophysics, Medical
Language
eng
Abstract
In vivo MR-imaging was also applied to study effects of neonatal, unilateral olfactory denervation on postnatal olfactory bulb growth. The in vivo imaging data were used to quantify the reduction in laminar volumes of the denervated bulb, compared to contralateral control bulb, unoperated normal rat bulbs and with corresponding histological sections. Lastly, serial 2-D in vivo MR-images were utilized to develop 3-D reconstructions of olfactory bulb and cavity micro-structure, in normal and neonatally denervated animals. The 3-D images offered improved flexibility in the analysis of large experimental imaging data-sets and rather detailed, well differentiated representation of various olfactory structures.
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