University of Illinois Urbana-Champaign

Analysis of the Mechanisms and Principles of Neural Development in the Drosophila

Hoang, Bao Quoc

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Description

Title
Analysis of the Mechanisms and Principles of Neural Development in the Drosophila
Author(s)
Hoang, Bao Quoc
Issue Date
2000
Doctoral Committee Chair(s)
Chiba, Akira
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Neuroscience
Language
eng
Abstract
In addition, this research began to uncover the possible principles that are applied to synaptic development. By systematically examining individual neuromuscular synapse in Drosophila, I observed key features of synaptic formation. Examining the motoneurons that formed different types of boutons showed variances in the innervation patterns produced by the motoneurons. The motoneurons that developed the large synapses (type Ib) innervated one target, while the motoneurons that formed the smaller synapses (type Is and type II) innervated multiple partners. I was also able to identify the bouton types that specific motoneurons formed. This may be used to correlate the motoneuron characters to the synapse formed. Lastly, I presented a situation of synaptic remodeling in Drosophila that can be used to study synaptic plasticity. This part of my research characterized a model system in which one can observe events of synaptic plasticity and differentiation with the resolution of an individual cell.
Graduation Semester
2000
Type of Resource
text
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http://hdl.handle.net/2142/86754

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Dissertations and Theses - Microbiology