In Vivo Studies of DNA Synthesis in Escherichia Coli Are Consistent With a Discontinuous Model of DNA Replication
Amado, Luciana
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Permalink
https://hdl.handle.net/2142/86715
Description
Title
In Vivo Studies of DNA Synthesis in Escherichia Coli Are Consistent With a Discontinuous Model of DNA Replication
Author(s)
Amado, Luciana
Issue Date
2010
Doctoral Committee Chair(s)
Kuzminov, Andrei
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Microbiology
Language
eng
Abstract
During our research we also found that the identification of replication intermediates in some cases has been mistaken by the presence of polyphosphate species. We show evidence that these polyphosphate species are not replication intermediates, and we go further into developing a simple method to analyze and quantify the accumulation of polyphosphates in E. coli cells.
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