Regulatory Mechanisms Controlling Expression of the Toll-Like Receptor 2 Subfamily
Johnson, Christopher Michael
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Permalink
https://hdl.handle.net/2142/86709
Description
Title
Regulatory Mechanisms Controlling Expression of the Toll-Like Receptor 2 Subfamily
Author(s)
Johnson, Christopher Michael
Issue Date
2008
Doctoral Committee Chair(s)
Richard Tapping
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Health Sciences, Immunology
Language
eng
Abstract
Therefore, this thesis describes three novel mechanisms controlling expression of TLR2 subfamily members---one acting at the level of transcriptional activation, another at the post-transcriptional level, and finally one that regulates the post-translational localization of the receptor. In chapter five, I will summarize these findings and discuss the potential implications.
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