Functional Studies of Acyl Carrier Protein and the Phosphopantetheinyl Transferase AcpT in Escherichia Coli K-12
Delay, Nicholas R.
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https://hdl.handle.net/2142/86693
Description
Title
Functional Studies of Acyl Carrier Protein and the Phosphopantetheinyl Transferase AcpT in Escherichia Coli K-12
Author(s)
Delay, Nicholas R.
Issue Date
2007
Doctoral Committee Chair(s)
Cronan, John E., Jr
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Microbiology
Language
eng
Abstract
Overexpression of AcpT was reported to suppress an E. coli K-12 mutant that has a temperature-sensitive phenotype and lipid A biosynthetic defect. I have mapped the mutation responsible for the lipid A biosynthetic defect and temperature-sensitive phenotype of this strain and have further characterized the suppression of the temperature-sensitive phenotype of strain LH530 by overexpression of AcpT.
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