Intracellular Dynamics of Hydrogen Peroxide in Escherichia Coli
Seaver, Lauren Costa
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https://hdl.handle.net/2142/86666
Description
Title
Intracellular Dynamics of Hydrogen Peroxide in Escherichia Coli
Author(s)
Seaver, Lauren Costa
Issue Date
2004
Doctoral Committee Chair(s)
Imlay, James A.
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Microbiology
Language
eng
Abstract
Surprisingly, additional experiments utilizing these scavenger-less mutants confirmed that the majority of endogenous H2O2 does not appear to be a result of the electron transport chain. However, these results did confirm that specific flavoenzymes, shown in vitro to make H 2O2, can autoxidize and adventitiously contribute to cytosolic H2O2 formation in vivo. However, the most substantial H2O2 generator remains unidentified.
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