The Ups and Downs of MAP Kinase ERK: Modulation of Molecular Responses to Song in the Zebra Finch Auditory Forebrain
Cheng, Hui-Yun
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https://hdl.handle.net/2142/86659
Description
Title
The Ups and Downs of MAP Kinase ERK: Modulation of Molecular Responses to Song in the Zebra Finch Auditory Forebrain
Author(s)
Cheng, Hui-Yun
Issue Date
2003
Doctoral Committee Chair(s)
Clayton, David F.
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Animal Physiology
Language
eng
Abstract
These studies demonstrate that ERK activity in the auditory forebrain reflects information about the familiarity and significance of a specific birdsong stimulus. Moreover, ERK activation appears to be necessary, but perhaps not sufficient, for triggering of an IEG response to song presentation. Thus ERK has a central role in connecting behavioral and perceptual experience to genomic mechanisms of learning and memory.
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