The Role of Coregulator Proteins in Nuclear Receptor Transcriptional Activity
Rajendran, Ramji Ramaswamy
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https://hdl.handle.net/2142/86653
Description
Title
The Role of Coregulator Proteins in Nuclear Receptor Transcriptional Activity
Author(s)
Rajendran, Ramji Ramaswamy
Issue Date
2003
Doctoral Committee Chair(s)
Katzenellenbogen, Benita S.
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Biochemistry
Language
eng
Abstract
This thesis reports studies in which I have characterized a novel DEAD box RNA helicase as a nuclear receptor coregulator. I have also examined the similarities in the actions of ERalpha and ERbeta using large-scale chromatin arrays and ER subtype-selective ligands.
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