A Structural and Functional Analysis of the Human Angiotensin II Type-2 Receptor
Moore, Steven Allen, Jr
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Permalink
https://hdl.handle.net/2142/86652
Description
Title
A Structural and Functional Analysis of the Human Angiotensin II Type-2 Receptor
Author(s)
Moore, Steven Allen, Jr
Issue Date
2003
Doctoral Committee Chair(s)
James Weyhenmeyer
Department of Study
Microbiology
Discipline
Microbiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Health Sciences, Pharmacology
Language
eng
Abstract
In the third series of experiments we used synthetic peptides derived from the amino acid sequence of the cytoplasmic loops and tail of the AT 2 receptor are used to determine what regions are important to G-protein activation. These studies will map the G-protein coupling regions of the human AT2 receptor and develop a wider understanding of AT2 receptor/G-protein interactions.
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