An Analysis of the Efficacy of Cervical Cancer Screening in Elderly Women
Maduram, David Thomas
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https://hdl.handle.net/2142/86391
Description
Title
An Analysis of the Efficacy of Cervical Cancer Screening in Elderly Women
Author(s)
Maduram, David Thomas
Issue Date
2007
Doctoral Committee Chair(s)
Rosenblatt, Karin
Department of Study
Kinesiology and Community Health
Discipline
Kinesiology and Community Health
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Gerontology
Language
eng
Abstract
Recent studies have failed to reach a consensus on whether Papanicolaou (Pap) smear screening tests should be administered to women aged 65 years and older. Our case-control study utilized 2,778 incident cervical cancer cases from the Surveillance, Epidemiology and End Results (SEER) program registries that were diagnosed between 1991 and 1999. Population controls (N=10,137) were matched on age and geographical location to cases and were identified through a random 5% sample of Medicare beneficiaries living in regions of the United States covered by the SEER program registries. Pap smear screening history information for cases and controls was ascertained from Medicare billing records. Estimates of population hysterectomy prevalence from the National Health Interview Survey (NHIS) were used to obtain a hysterectomy-adjusted estimate of screening efficacy, controlled for race and education (OR = 0.39, CI = 0.33-0.44). Further analyses illustrated that cervical cancer screening had a negative association for women of all age groups, including women aged 65-75 (OR = 0.23, CI = 0.14-0.34), women aged 75-85 (OR = 0.48, CI = 0.38-0.61) and women aged 85 and above (OR = 0.45, CI = 0.29-0.70). In addition, analyses stratified on cancer stage showed that the Pap smear cervical cancer screening had a stronger negative association.
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