FTIR Difference Spectroscopy Studies on Membrane Proteins
Vakkasoglu, Ahmet Selim
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https://hdl.handle.net/2142/85474
Description
Title
FTIR Difference Spectroscopy Studies on Membrane Proteins
Author(s)
Vakkasoglu, Ahmet Selim
Issue Date
2008
Doctoral Committee Chair(s)
Gennis, Robert B.
Department of Study
Biophysics and Computational Biology
Discipline
Biophysics and Computational Biology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Analytical
Language
eng
Abstract
Fourier Transform Infrared Spectrsocopy (FTIR) is a powerful technique that is well suited to the investigation of protonation/deprotonation reactions of individual side chains within proteins, as well as any changes that might occur in the strength of H-bonds any change in the overall protein structure. The method can be applied in a static manner, revealing differences between two defined states of a protein, or can be done in a time-dependent manner in the microsecond/millisecond time range.
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