Folding Thermodynamic and Kinetic Characterization of Small Model Proteins: Lambda Repressor, U1A, Trpzip2 and PAO -12
Yang, Wei Yuan
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https://hdl.handle.net/2142/85434
Description
Title
Folding Thermodynamic and Kinetic Characterization of Small Model Proteins: Lambda Repressor, U1A, Trpzip2 and PAO -12
Author(s)
Yang, Wei Yuan
Issue Date
2003
Doctoral Committee Chair(s)
Martin Gruebele
Department of Study
Biophysics and Computational Biology
Discipline
Biophysics and Computational Biology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Molecular
Language
eng
Abstract
Complete prediction of the folding processes for complex protein molecules through first principles is currently not possible (2003). Here we take an empirical approach towards a better understanding of the protein-folding problem, through thermodynamic and kinetic characterizations of several small model proteins. We were able to identify many complex behaviors that have not previously been seen.
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