Regulation of Energy Metabolism by Fructose in the Liver
Koo, Hyun-Young
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https://hdl.handle.net/2142/84956
Description
Title
Regulation of Energy Metabolism by Fructose in the Liver
Author(s)
Koo, Hyun-Young
Issue Date
2008
Doctoral Committee Chair(s)
John W. Erdman, Jr.
Department of Study
Nutritional Sciences
Discipline
Nutritional Sciences
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Health Sciences, Nutrition
Language
eng
Abstract
In conclusion, fructose feeding induced a broader range of genes than previously identified with simultaneous increase in glycogen and triglycerides in liver. SREBP-1 and ChREBP, and possibly FoxO1, likely mediate gene induction by dietary fructose. The study also suggests that further ChREBP activation occurs in the nucleus after nuclear translocation of ChREBP in F-fed rat.
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