Insight Into the Metabolism of Lycopene: Focus on Androgen -Dependent Tissues
Zaripheh, Susan
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https://hdl.handle.net/2142/84943
Description
Title
Insight Into the Metabolism of Lycopene: Focus on Androgen -Dependent Tissues
Author(s)
Zaripheh, Susan
Issue Date
2005
Doctoral Committee Chair(s)
John W. Erdman, Jr.
Department of Study
Nutritional Sciences
Discipline
Nutritional Sciences
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Health Sciences, Nutrition
Language
eng
Abstract
This research has shown that lyc metabolites accumulate in the prostate, seminal vesicles and adrenal gland compared to the other analyzed tissues. Moreover, modulated carotenoid cleavage enzyme(s) expression in the adrenal, prostate and kidney suggested that the accumulated lyc metabolites in these tissues be involved in the observed transcriptional changes. In essence, lyc has previously been reported to improve antioxidant status but the presented data suggests that lyc could also modulate prostate cancer related genes.
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