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https://hdl.handle.net/2142/84887
Description
Title
Engineering Antibodies to Control T Cell Function
Author(s)
Cho, Bryan Kenneth
Issue Date
1997
Doctoral Committee Chair(s)
Kranz, David M.
Department of Study
Biochemistry
Discipline
Biochemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Molecular
Language
eng
Abstract
In Chapter Five, a yeast display system was used to show that a T cell receptor ligand (scFv-KJ16) expressed on the surface of yeast was capable of inducing T cell activation. These findings suggest that the yeast display system can be used to discover novel polypeptides that regulate biological functions through cell to cell interactions.
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