Fast Processes in Heme Proteins: Mechanisms of Electron Transfer and Carbon Monoxide Recombination
McClean, Mark Andrew
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Permalink
https://hdl.handle.net/2142/84878
Description
Title
Fast Processes in Heme Proteins: Mechanisms of Electron Transfer and Carbon Monoxide Recombination
Author(s)
McClean, Mark Andrew
Issue Date
1997
Doctoral Committee Chair(s)
Sligar, Stephen G.
Department of Study
Biochemistry
Discipline
Biochemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Biochemistry
Language
eng
Abstract
An in depth study of carbon monoxide recombination to cytochrome P450$\sb{\rm BM{-}3}$ has shown that this enzyme undergoes a conformational change upon substrate binding. The dynamics of the active site are probed through analysis of the geminate recombination in the presence and absence of substrate.
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