Estrogen Receptor Dependent Gene Regulation in Human Breast Cancer Cells
Stender, Joshua David
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Permalink
https://hdl.handle.net/2142/84852
Description
Title
Estrogen Receptor Dependent Gene Regulation in Human Breast Cancer Cells
Author(s)
Stender, Joshua David
Issue Date
2008
Doctoral Committee Chair(s)
Katzenellenbogen, Benita S.
Department of Study
Biochemistry
Discipline
Biochemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Biochemistry
Language
eng
Abstract
These studies provide new insights into gene regulation by the estrogen receptor and cooperating factors such as PITX1. They also highlight the importance of this nuclear hormone receptor in controlling cellular functions including proliferation of breast cancer cells. These studies should assist in the development of novel targeted therapies for breast cancer prevention and treatment.
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