Deoxyribozyme-Mediated Synthesis of Branched and Lariat RNAs and Their Application in Studying Group II Intron's Splicing Mechanisms
Wang, Yangming
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https://hdl.handle.net/2142/84829
Description
Title
Deoxyribozyme-Mediated Synthesis of Branched and Lariat RNAs and Their Application in Studying Group II Intron's Splicing Mechanisms
Author(s)
Wang, Yangming
Issue Date
2006
Doctoral Committee Chair(s)
Silverman, Scott K.
Department of Study
Biochemistry
Discipline
Biochemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Molecular
Language
eng
Abstract
Finally, a general strategy to synthesize 5'-adenylated RNA using T4 DNA ligase was developed. 5'-Adenylated RNA can be used for in vitro selection to identify deoxyribozymes with new activities.
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