Structural and Biochemical Studies of the Innate Immune Pathway
Lasker, Michael Virnelson
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https://hdl.handle.net/2142/84825
Description
Title
Structural and Biochemical Studies of the Innate Immune Pathway
Author(s)
Lasker, Michael Virnelson
Issue Date
2006
Doctoral Committee Chair(s)
Satish Nair
Department of Study
Biochemistry
Discipline
Biochemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Health Sciences, Immunology
Language
eng
Abstract
Investigating the biochemical properties of the IRAK-4 DD led to a series of molecular recognition experiments with MyD88. In vitro transcription and translation pull-down experiments performed with IRAK-4 DD and MyD88 suggest that the ID of MyD88 might mediate this interaction.
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