Engineering Myoglobin Into Both a Structural and Functional Model of Nitric Oxide Reductase
Yeung, Natasha H.
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https://hdl.handle.net/2142/84330
Description
Title
Engineering Myoglobin Into Both a Structural and Functional Model of Nitric Oxide Reductase
Author(s)
Yeung, Natasha H.
Issue Date
2008
Doctoral Committee Chair(s)
Lu, Yi
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Biochemistry
Language
eng
Abstract
To date, FeBMb is the first protein model of the FeB site of NOR and provides the first evidence, from an NOR model, that the identity of the metal in analogous non-heme metal binding sites of HCO (i.e., CuB) and NOR (i.e., FeB) can tune NO activity. In summary, FeBMb is both a structural and functional model of NOR. (Abstract shortened by UMI.).
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