Colorimetric Sensor Array: Do I See What You Smell
Ponder, Jennifer B.
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https://hdl.handle.net/2142/84244
Description
Title
Colorimetric Sensor Array: Do I See What You Smell
Author(s)
Ponder, Jennifer B.
Issue Date
2006
Doctoral Committee Chair(s)
Kenneth S. Suslick
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Microbiology
Language
eng
Abstract
We have developed and patented a unique chemical detection technology in which colorimetric changes in an array of dyes constitute a signal much like that generated by the mammalian olfaction system; each dye is a cross-responsive sensor. This technology uses a disposable printed array of chemically responsive dyes as the primary sensor elements. The dyes undergo reversible reactions that result in well defined color changes due to stronger chemical interactions: ligation to metal ions, Lewis or Bronsted acid-base interactions, hydrogen bonding, etc. Striking visual identification of a wide range of VOCs are easily made at part per billion (ppb) levels with extremely low error rates for Toxic Industrial Chemicals (TICs) at both their IDLH (Immediately Dangerous to Life or Health) and the much more demanding PEL (workday permissible exposure limits). Complex mixtures are easily identified, such as coffees and perfumes, making this technology ideal for quality control applications. This technology is also used for the detection and identification of pathogenic bacterium based on volatile metabolites emitted during growth.
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