Interrogation of Yeast Responses to Anaerobic Growth Conditions at the Intact Protein Level Using Improved Top-Down Proteomics
Du, Yi
This item is only available for download by members of the University of Illinois community. Students, faculty, and staff at the U of I may log in with your NetID and password to view the item. If you are trying to access an Illinois-restricted dissertation or thesis, you can request a copy through your library's Inter-Library Loan office or purchase a copy directly from ProQuest.
Permalink
https://hdl.handle.net/2142/84209
Description
Title
Interrogation of Yeast Responses to Anaerobic Growth Conditions at the Intact Protein Level Using Improved Top-Down Proteomics
Author(s)
Du, Yi
Issue Date
2005
Doctoral Committee Chair(s)
Kelleher, Neil L.
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Analytical
Language
eng
Abstract
Taking advantage of further development of the front-end platform and metabolic labeling quantitative strategy, top-down proteomics was employed to investigate the response of Saccharomyces cerevisiae towards anaerobiosis. Approximately 150 protein pairs were measured with 4 differential expressions determined including an aerobic and anaerobic isoform. Direct comparison of PTM patterns between two cell states was also accomplished through top-down proteomics.
Use this login method if you
don't
have an
@illinois.edu
email address.
(Oops, I do have one)
IDEALS migrated to a new platform on June 23, 2022. If you created
your account prior to this date, you will have to reset your password
using the forgot-password link below.
