University of Illinois Urbana-Champaign

Modified Farnesyl Diphosphate, Germacrane, and Eremophilane Sesquiterpenes as Probes for Capsidiol *Biosynthesis

Zhao, Yuxin

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Description

Title
Modified Farnesyl Diphosphate, Germacrane, and Eremophilane Sesquiterpenes as Probes for Capsidiol *Biosynthesis
Author(s)
Zhao, Yuxin
Issue Date
2005
Doctoral Committee Chair(s)
Coates, Robert M.
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Organic
Language
eng
Abstract
The final part of this thesis discusses the preparation and characterization of two deoxycapsidiols as well as a series of capsidiol analogs including epiaristolochene and two isomers. Overall, ten capsidiol derivatives were synthesized from capsidiol and sent to collaborators for various biological evaluations. In addition, this library was evaluated for antifungal activity in order to establish preliminary structure-activity relationships.
Graduation Semester
2005
Type of Resource
text
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http://hdl.handle.net/2142/84208

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