University of Illinois Urbana-Champaign

Probing Biological Systems at the Single Molecule Level: Studies of the Homophilic Binding of the Neural Cell Adhesion Molecule (Ncam) and Phase Dependent Lipid Anchorage Strength

Wieland, Julie A.

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https://hdl.handle.net/2142/84204

Description

Title
Probing Biological Systems at the Single Molecule Level: Studies of the Homophilic Binding of the Neural Cell Adhesion Molecule (Ncam) and Phase Dependent Lipid Anchorage Strength
Author(s)
Wieland, Julie A.
Issue Date
2005
Doctoral Committee Chair(s)
  • Gewirth, Andrew A.
  • Leckband, Deborah E.
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Analytical
Language
eng
Abstract
Force probe measurements were also used to study environmental effects on the intermolecular strength of lipids within a membrane. In this case the anchorage strength of lipids in fluid versus gel lipid layers was probed to determine how temperature affects the adhesion properties between adjacent lipid molecules. From this study we have shown that it takes almost three times the force to extract a lipid from a gel phase lipid layer as opposed a fluid phase layer.
Graduation Semester
2005
Type of Resource
text
Permalink
http://hdl.handle.net/2142/84204

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