Mass Spectrometric Studies of Nonribosomal, Enzymatic Assembly of Natural Products Through Thiotemplate Biosynthesis
Mazur, Matthew Thomas
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https://hdl.handle.net/2142/84158
Description
Title
Mass Spectrometric Studies of Nonribosomal, Enzymatic Assembly of Natural Products Through Thiotemplate Biosynthesis
Author(s)
Mazur, Matthew Thomas
Issue Date
2004
Doctoral Committee Chair(s)
Kelleher, Neil L.
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Chemistry, Biochemistry
Language
eng
Abstract
This is the first in-depth application of FTMS to the study of NRP/PKS enzymes for the elucidation of natural product biosynthesis. The reliance of FTMS will continue to improve and should prove itself worthy of the best analytical assay tool for uncovering the intricate mechanisms of thiotemplate enzymes.
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