University of Illinois Urbana-Champaign

Off-Line CE/MALDI MS: Sampling and Deposition Techniques to Incorporate Complementary Analyses for Cellular Assays

Page, Jason Steven

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https://hdl.handle.net/2142/84087

Description

Title
Off-Line CE/MALDI MS: Sampling and Deposition Techniques to Incorporate Complementary Analyses for Cellular Assays
Author(s)
Page, Jason Steven
Issue Date
2002
Doctoral Committee Chair(s)
Sweedler, Jonathan V.
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Neuroscience
Language
eng
Abstract
The viability of this CE/MS method is demonstrated by the chemical profiling of tissues and single cells from the marine mollusc, Aplysia californica , assaying neuronal release, analyzing cone snail venoms, and incorporating radionuclide detection with CE/MALDI MS. The application of the CE/MS technique toward the analysis of these samples shows that this method is capable of analyzing the neuropeptides in single neurons, and it is also amendable to a wide variety of other areas where there is need to get more information from mass-limited samples.
Graduation Semester
2002
Type of Resource
text
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http://hdl.handle.net/2142/84087

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