University of Illinois Urbana-Champaign

The Development of Microfluidic Devices Fabricated From Poly(dimethyl) Siloxane

Monahan, Jennifer

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Description

Title
The Development of Microfluidic Devices Fabricated From Poly(dimethyl) Siloxane
Author(s)
Monahan, Jennifer
Issue Date
2001
Doctoral Committee Chair(s)
  • Gewirth, Andrew A.
  • Nuzzo, Ralph G.
Department of Study
Chemistry
Discipline
Chemistry
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Engineering, Materials Science
Language
eng
Abstract
"This dissertation outlines work in the field of polymeric microfluidic (muFL) devices, particularly the design and fabrication of microfluidic devices using poly(dimethyl) siloxane (PDMS). Fabrication involved lithographic and ""soft"" lithographic techniques. Capillary electrophoretic separation ""chips"" as well as a series of patterns for surface functionalization were demonstrated in PDMS. PDMS proved to be a unique medium for high pH separations allowing the electrophoretic separation of un-derivatized sugars coupled with indirect fluorescence detection. A new microfluidic design for built-in standardization of chip-based separations is also discussed. During the course of this work, a novel method for filling hydrophobic microfluidic capillaries was developed, Capillary Outgas Technique (COT). COT was coupled with surface immobilization and wet etching techniques to generate patterned surfaces."
Graduation Semester
2001
Type of Resource
text
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http://hdl.handle.net/2142/84048

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