Design, Fabrication, and Test of Chaotic Micromixers, Hydrogel Microvalves and pH Regulation Systems
Liu, Hui
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https://hdl.handle.net/2142/84016
Description
Title
Design, Fabrication, and Test of Chaotic Micromixers, Hydrogel Microvalves and pH Regulation Systems
Author(s)
Liu, Hui
Issue Date
2001
Doctoral Committee Chair(s)
David J. Beebe
Department of Study
Mechanical Engineering
Discipline
Mechanical Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Engineering, Mechanical
Language
eng
Abstract
In the last part of the thesis, two integrated microsystems designed to provide self regulation of pH in bioassays are demonstrated. The first system is based on the counterflow microdialysis principle, whereas the second system involves direct addition of an acidic or basic buffer solution into a sample solution. In both systems, a hydrogel component is used as a pH sensor, controller, and valve, simultaneously. Oscillatory modulation of the flow was achieved, and the feasibility of autonomous control of pH in microsystems has been demonstrated.
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