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https://hdl.handle.net/2142/83549
Description
Title
Effects of Leptin on the Rat Cervix
Author(s)
Baumgartner, William Wade
Issue Date
2003
Doctoral Committee Chair(s)
Bahr, Janice M.
Department of Study
Animal Sciences
Discipline
Animal Sciences
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Cell
Language
eng
Abstract
The investigations conducted indicate that leptin, in the presence of relaxin and estrogen, increases cervical extensibility, wet weight and dry weight. Leptin also is capable of increasing cellular proliferation and collagen accumulation in the cervix. However, the studies conducted indicate that leptin may not modulate the extra-cellular matrix through matrix metalloproteinases, but leptin appears to play a role in the disorganization of collagen fibers.
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