The Effects of Lactational and Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin or Coplanar PCBs on Spatial Learning and Memory

Seo, Byung-Woun

Permalink

https://hdl.handle.net/2142/82539 Copy

Description

Title

The Effects of Lactational and Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin or Coplanar PCBs on Spatial Learning and Memory

Author(s)

Seo, Byung-Woun

Issue Date

1999

Doctoral Committee Chair(s)

Schantz, Susan L.

Department of Study

Neuroscience

Discipline

Neuroscience

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

Ph.D.

Degree Level

Dissertation

Date of Ingest

2015-09-25T20:45:45Z

Keyword(s)

Psychology, Psychobiology

Language

eng

Abstract

One way in which rats are able to solve the RAM without employing memory systems is by using a response strategy. The most obvious response strategy that would yield better performance on the RAM is adjacent arm selection. A final study was conducted, in which TCDD-exposed animals were tested on the 8-arm RAM with all of the arms baited or on the 12-arm RAM with only 8 of the 12 arms baited. It was hypothesized that if TCDD-exposed rats had better memory, they should show improvements relative to controls on both tasks. The final study again replicated the reduction in errors on the 8-arm RAM in the TCDD-exposed animals. However, the TCDD-exposed rats did not differ from the controls on the 12-arm RAM. These results suggested that the TCDD-exposed rats were using a response strategy to solve the 8-arm RAM task, but surprisingly there was no indication of increased adjacent arm patterning in these animals. It was concluded that the TCDD-exposed animals probably do not have enhanced spatial memory. (Abstract shortened by UMI.).

Graduation Semester

1999

Type of Resource

text

Permalink

http://hdl.handle.net/2142/82539

Owning Collections