University of Illinois Urbana-Champaign

The Effects of Lactational and Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin or Coplanar PCBs on Spatial Learning and Memory

Seo, Byung-Woun

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https://hdl.handle.net/2142/82539

Description

Title
The Effects of Lactational and Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin or Coplanar PCBs on Spatial Learning and Memory
Author(s)
Seo, Byung-Woun
Issue Date
1999
Doctoral Committee Chair(s)
Schantz, Susan L.
Department of Study
Neuroscience
Discipline
Neuroscience
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Psychology, Psychobiology
Language
eng
Abstract
One way in which rats are able to solve the RAM without employing memory systems is by using a response strategy. The most obvious response strategy that would yield better performance on the RAM is adjacent arm selection. A final study was conducted, in which TCDD-exposed animals were tested on the 8-arm RAM with all of the arms baited or on the 12-arm RAM with only 8 of the 12 arms baited. It was hypothesized that if TCDD-exposed rats had better memory, they should show improvements relative to controls on both tasks. The final study again replicated the reduction in errors on the 8-arm RAM in the TCDD-exposed animals. However, the TCDD-exposed rats did not differ from the controls on the 12-arm RAM. These results suggested that the TCDD-exposed rats were using a response strategy to solve the 8-arm RAM task, but surprisingly there was no indication of increased adjacent arm patterning in these animals. It was concluded that the TCDD-exposed animals probably do not have enhanced spatial memory. (Abstract shortened by UMI.).
Graduation Semester
1999
Type of Resource
text
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http://hdl.handle.net/2142/82539

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