Amygdalar Modulation of the Medial Geniculate Nucleus and Cingulate Cortex in Discriminative Avoidance Training
Kashef, Alireza
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https://hdl.handle.net/2142/82513
Description
Title
Amygdalar Modulation of the Medial Geniculate Nucleus and Cingulate Cortex in Discriminative Avoidance Training
Author(s)
Kashef, Alireza
Issue Date
2007
Doctoral Committee Chair(s)
Gabriel, Michael
Department of Study
Neuroscience
Discipline
Neuroscience
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Psychology, Behavioral
Language
eng
Abstract
Neurons in A29 and the lateral nucleus of the amygdala (LA) characteristically develop maximal dTIA in late stages of DAL. Experiment II tested the hypothesis that LA nucleus is responsible for the late dTIA in A29. As hypothesized, LA nuclear excitotoxic lesions decreased dTIA in A29. Moreover, A29 theta-like neuronal activity was weaker in these subjects. Not in accord with the hypothesis, LA nuclear lesions impaired the early developing dTIA in A24. Thus, the LA nucleus may contribute to dTIA induction in A24, or the lesion may have damaged regions outside of the LA nucleus. Taken together these studies add significantly to understanding amygdalar modulation of neurons in extra-amygdalar regions of the neural circuitry for DAL.
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