Transport-Kinetic Processes and Surface Chemistry in Biosensor Design
Vijayendran, Ravi Albert
This item is only available for download by members of the University of Illinois community. Students, faculty, and staff at the U of I may log in with your NetID and password to view the item. If you are trying to access an Illinois-restricted dissertation or thesis, you can request a copy through your library's Inter-Library Loan office or purchase a copy directly from ProQuest.
Permalink
https://hdl.handle.net/2142/82485
Description
Title
Transport-Kinetic Processes and Surface Chemistry in Biosensor Design
Author(s)
Vijayendran, Ravi Albert
Issue Date
2001
Doctoral Committee Chair(s)
Leckband, Deborah E.
Department of Study
Chemical Engineering
Discipline
Chemical Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Engineering, Biomedical
Language
eng
Abstract
"Finally, sample mixing is examined as a potential method to improve the performance of microfluidic biosensors. We attempt to mix sections of the sample solution where the analyte concentration is high with other sections where it is low, and thereby reduce the sensor response time when the detection kinetics are diffusion-limited. A serpentine micromixer, originally designed to mix two fluids in bulk solution via ""chaotic advection,"" is used to mix the sample as it passes through a surface plasmon resonance biosensor. These experiments indicate that such ""solution-based"" mixing strategies can be effective in microfluidic biosensors."
Use this login method if you
don't
have an
@illinois.edu
email address.
(Oops, I do have one)
IDEALS migrated to a new platform on June 23, 2022. If you created
your account prior to this date, you will have to reset your password
using the forgot-password link below.
