Regulation of Hexose and Pentose Metabolism by Escherichia Coli
Desai, Tasha A.
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Permalink
https://hdl.handle.net/2142/82428
Description
Title
Regulation of Hexose and Pentose Metabolism by Escherichia Coli
Author(s)
Desai, Tasha A.
Issue Date
2009
Doctoral Committee Chair(s)
Christopher Rao
Department of Study
Chemical Engineering
Discipline
Chemical Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Engineering, Chemical
Language
eng
Abstract
Collectively, the results from my research have identified that E. coli employs a complex cellular control system in order to selectively process individual sugars. By identifying the mechanism for this control, I have identified specific genetic targets for subsequent metabolic engineering. This discovery will enable the construction of E. coli strains capable of simultaneously and efficiently processing mixtures of hexose and pentose sugars. These strains will likely have application in biotechnology and also potentially in the production of cellulosic biofuels.
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