The Neurobiology of Motor Skill Learning: Structural Adaptation Within Sensorimotor Regions of the Rat Brain
Kleim, Jeffrey Allan
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https://hdl.handle.net/2142/82211
Description
Title
The Neurobiology of Motor Skill Learning: Structural Adaptation Within Sensorimotor Regions of the Rat Brain
Author(s)
Kleim, Jeffrey Allan
Issue Date
1997
Doctoral Committee Chair(s)
Greenough, William T.
Department of Study
Psychology
Discipline
Psychology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Neuroscience
Language
eng
Abstract
A second series of studies revealed the AC animals to have significantly more synapses/neuron within layer II/III of the motor cortex than control animals and that this difference was dependent on the amount of training the animals received. Changes in synapse morphology were also observed in the AC animals that included significant increases in postsynaptic density (PSD) length, number of synapses with perforated PSDs as well as number of synapses forming multiple synaptic contacts. Finally, an examination of the gross morphology of the red nucleus revealed no significant change in neuronal density which is believed to indicate no overall change in neuronal morphology.
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