Biological Mimics: A New Paradigm in the Detection of Toxic Compounds
Monty, Chelsea Nicole
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Permalink
https://hdl.handle.net/2142/81146
Description
Title
Biological Mimics: A New Paradigm in the Detection of Toxic Compounds
Author(s)
Monty, Chelsea Nicole
Issue Date
2009
Doctoral Committee Chair(s)
Masel, Richard I.
Department of Study
Electrical Engineering
Discipline
Electrical Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Engineering, Chemical
Language
eng
Abstract
The techniques reported in this thesis can be then be expanded to mimic other biological molecules and processes. Mimic sensors could be developed for other common toxicological modes, for example, oxidative stress and phosphorylation inhibitors. The ability to detect toxins using biological mimics allows for creation of toxicity assays with the selectivity of biomolecules and the stability of chemical compounds. Other mimic sensors can be developed using the NIBS detection scheme to create a library of sensitive, selective, and portable detectors for a variety of toxin.
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