New Developments on Quantitative Imaging Using Ultrasonic Waves
Lavarello Montero, Roberto Janniel
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https://hdl.handle.net/2142/81141
Description
Title
New Developments on Quantitative Imaging Using Ultrasonic Waves
Author(s)
Lavarello Montero, Roberto Janniel
Issue Date
2009
Doctoral Committee Chair(s)
Oelze, Michael L.
Department of Study
Electrical and Computer Engineering
Discipline
Electrical and Computer Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Engineering, Electronics and Electrical
Language
eng
Abstract
Although ultrasound imaging is widely used for medical applications, conventional sonographic B-mode images are qualitative. As a consequence, medical diagnosis using sonograms is commonly subjective and depends on the expertise of the operator. The need to obtain quantitative information from tissues resulted in the development of alternative ways of processing the radiofrequency ultrasonic data. Two notable approaches are acoustic tomography and backscatter coefficient analysis. However, these techniques suffer from limitations that keep them from becoming widely used clinical tools. This dissertation presents several developments relevant to quantitative ultrasonic imaging using both acoustic tomography and backscatter coefficient analysis. First, a regularization method was developed to improve on the computational stability of acoustic tomography. The use of multiple frequency information to extend the region of convergence of acoustic tomography was validated experimentally. Second, the feasibility of obtaining quantitative density information (which is usually neglected in acoustic tomography) was explored. The practical limitations and convergence of existing density imaging approaches were studied, and improved algorithmic variations were developed and characterized. Third, two approaches for three-dimensional acoustic tomography were studied through simulations with emphasis on the effect of sensor topologies on the quality of the reconstructions. Finally, potential benefits of using an acoustic tomography scanner in conjunction with backscatter coefficient analysis were explored through simulations and experiments by performing full angular compounding and using acoustic tomograms for refraction correction.
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