Investigation of Uniform Biomaterial-Based Microspheres With Precisely Controlled Size and Size Distribution for Development of Advanced Drug Delivery Systems

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https://hdl.handle.net/2142/80971

Title: Investigation of Uniform Biomaterial-Based Microspheres With Precisely Controlled Size and Size Distribution for Development of Advanced Drug Delivery Systems
Author(s): Choy, Young Bin
Issue Date: 2006
Doctoral Committee Chair(s): Kyekyoon (Kevin) Kim
Department of Study: Electrical and Computer Engineering
Discipline: Electrical and Computer Engineering
Degree Granting Institution: University of Illinois at Urbana-Champaign
Degree Name: Ph.D.
Degree Level: Dissertation
Keyword(s): Engineering, Materials Science
Language: eng
Abstract: Uniform chitosan MS (CMS) were employed for precisely controlled delivery of acidic drug, where colon-specific delivery could be realized without any additive polymers or toxic process. For strong acidic drug, the smaller the CMS, the more drugs could be contained until the colonic site hence the better candidate for colon-specific delivery. Weak acidic drug preferred the larger CMS due to the smaller amount of release at the gastric fluid.
Graduation Semester: 2006
Type of Resource: text
Permalink: http://hdl.handle.net/2142/80971