Simultaneous Integrated Functional Magnetic Resonance Imaging and Optical Tomography in the Near Infrared Spectrum (Sinfonis) for Studying Hemodynamic and Neuronal Responses in the Human Brain
Zhang, Xiaofeng
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https://hdl.handle.net/2142/80941
Description
Title
Simultaneous Integrated Functional Magnetic Resonance Imaging and Optical Tomography in the Near Infrared Spectrum (Sinfonis) for Studying Hemodynamic and Neuronal Responses in the Human Brain
Author(s)
Zhang, Xiaofeng
Issue Date
2005
Doctoral Committee Chair(s)
Andrew G. Webb
Department of Study
Electrical Engineering
Discipline
Electrical Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Psychology, Cognitive
Language
eng
Abstract
The hemodynamic responses reconstructed from DOT have shown reasonably good consistency with that of the BOLD fMRI result. It has been discovered from the correspondence between the two results that the change in oxyhemoglobin concentration may also play a secondary role in the BOLD signal. However, this hypothesis needs further systematic studies, such as determining the effect of oxyhemoglobin on the gradient of the extravascular magnetic susceptibility and its subsequent effect on T2*.
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