University of Illinois Urbana-Champaign

Magnetic Resonance Microscopy: 1. Four-Dimensional Spectral-Spatial Imaging. 2. Diffusional Effects in Magnetic Resonance Microscopy

Hyslop, William Brian

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Description

Title
Magnetic Resonance Microscopy: 1. Four-Dimensional Spectral-Spatial Imaging. 2. Diffusional Effects in Magnetic Resonance Microscopy
Author(s)
Hyslop, William Brian
Issue Date
1998
Doctoral Committee Chair(s)
  • Lauterbur, Paul C.
  • Bob Clegg
Department of Study
Physics
Discipline
Physics
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biophysics, Medical
Language
eng
Abstract
DESIRE (Diffusionally-Enhanced Signal Intensity and REsolution) is a new method for nuclear magnetic resonance (NMR) microscopy which couples a spatially localized region of saturated magnetization to the surrounding medium via translational diffusion of spins, resulting in amplification of the total saturated magnetization by several orders of magnitude over that obtained in the absence of diffusion. Combined with signal detection at narrow bandwidths of the order of the transverse relaxation rate, DESIRE results in greatly increased signal-to-noise relative to traditional NMR imaging techniques and has the potential for submicron resolution. Both time-dependent and steady-state simulations and analytic expressions will be presented, as well as a one-dimensional DESIRE experiment.
Graduation Semester
1998
Type of Resource
text
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http://hdl.handle.net/2142/80656

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