University of Illinois Urbana-Champaign

Physical fitness and cardiovascular function in multiple sclerosis

Platta, Matthew E.

Content Files
PLATTA-THESIS-2015.pdf

Permalink

https://hdl.handle.net/2142/78550

Description

Title
Physical fitness and cardiovascular function in multiple sclerosis
Author(s)
Platta, Matthew E.
Issue Date
2015-04-30
Department of Study
Kinesiology & Community Health
Discipline
Kinesiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
M.S.
Degree Level
Thesis
Date of Ingest
2015-07-22T22:18:10Z
Keyword(s)
  • multiples sclerosis
  • exercise
  • respiratory fitness
  • muscular fitness
  • fitness
  • arterial function
  • cardiovascular
Abstract
Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease that affects the central nervous system. Cardiovascular function (CV) has been shown to be impaired in persons with MS which can lead to the development of comorbidities that can promote disability progression. Cardiorespiratory fitness (CRF) and, to a lesser extent, muscular fitness (MF) have been shown to improve CV function in healthy populations. This thesis examined the relationships between CRF, MF, and exercise presented by randomized controlled trials via meta-analysis. Then, the relationships between CRF, MF, and CV function in persons with MS was determined in order to determine targets for therapy that might improve CV function. Results suggest exercise training improved CRF and MF in RCTs of exercise training examining CRF and MF outcomes. Further, the results of this cross-sectional study indicate significant relationships exist between CRF, MF and CV function in persons with MS. These studies support the potential to improve physiological fitness through exercise training as a possible means to improve CV function in persons with MS. This might be accomplished through exercise training interventions involving aerobic and/or resistance exercise.
Graduation Semester
2015-5
Type of Resource
text
Permalink
http://hdl.handle.net/2142/78550
Copyright and License Information
Copyright 2015 Matthew Platta

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Graduate Dissertations and Theses at Illinois PRIMARY
Graduate Theses and Dissertations at Illinois
Dissertations and Theses - Kinesiology and Community Health