The Effects of Atropine Sulfate on Flight Simulator Performance and on Respiratory-Heart Period Interactions (Human, Electrocardiogram, Organophosphorous)

Dellinger, John Albert

Permalink

https://hdl.handle.net/2142/71317 Copy

Description

Title

The Effects of Atropine Sulfate on Flight Simulator Performance and on Respiratory-Heart Period Interactions (Human, Electrocardiogram, Organophosphorous)

Author(s)

Dellinger, John Albert

Issue Date

1984

Department of Study

Veterinary Medical Science

Discipline

Veterinary Medical Science

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

Ph.D.

Degree Level

Dissertation

Keyword(s)

Health Sciences, Pharmacology

Abstract

• Atropine sulfate is an important therapeutic agent for treating anticholinesterase toxicosis, but atropine also is a strong anticholinergic drug with side effects. Twenty volunteers received a placebo control and atropine doses of 0.5, 1.0, 2.0, and 4.0 mg/75 kg in a Latin Square double blind design, and effects were monitored for 3 hr post-injection.
• Primary task performance on six root mean square errors were tested in a multivariate analysis of variance, and the treatment effect was significant (F(24, 1236) = 5.95, p .10), (b) "difficulty swallowing," ED50 = 2.11 mg ((chi)('2)(1, N = 4) = 2.11, p > .10), (c) tachycardia, ED50 = 2.58 mg ((chi)('2)(1, N = 4) = 2.74, p .10), (e) photophobia, ED50 = 4.28 mg ((chi)('2)(1, N = 4) = 4.38, p .10).

Graduation Semester

1984

Type of Resource

text

Permalink

http://hdl.handle.net/2142/71317

Owning Collections