The Development of Coulostatic Charge Injection Techniques for High Performance Liquid Chromatography Analysis (Electrochemistry, Detection, Amperometry, Hplc)

Barnes, Anthony Charles

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Description

Title

The Development of Coulostatic Charge Injection Techniques for High Performance Liquid Chromatography Analysis (Electrochemistry, Detection, Amperometry, Hplc)

Author(s)

Barnes, Anthony Charles

Issue Date

1984

Department of Study

Chemistry

Discipline

Chemistry

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

Ph.D.

Degree Level

Dissertation

Keyword(s)

Chemistry, Analytical

Abstract

• The use of coulostatic charge injection techniques for the detection of electroactive species separated using high performance liquid chromatography is examined. The techniques examined include the single pulse technique in which the slope of the potential decay is correlated to concentration and the coulostatic pulse amperometric technique in which coulostatic pulses are used to mimic controlled potential amperometry. The single pulse technique gives detection limits of 2 x 10('-10) moles Pb(II) at a mercury electrode. Coulostatic pulse amperometry methods were used to quantitate 4 x 10('-11) moles of caffeic acid at a carbon paste electrode.
• The coulostatic pulse amperometric technique was also used to scan potential during analyte elution. Qualitative information (E(, 1/2) values) was gathered for both aminophenols and chlorophenols separated under reverse phase HPLC conditions. The half wave potentials were found to correspond closely to the values found using voltammetry in a still solution.

Graduation Semester

1984

Type of Resource

text

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http://hdl.handle.net/2142/70231

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