Bioactivities of Antiestrogens and Antiestrogen Metabolites in the Rat and Mouse
Hayes, James Roger
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Permalink
https://hdl.handle.net/2142/68310
Description
Title
Bioactivities of Antiestrogens and Antiestrogen Metabolites in the Rat and Mouse
Author(s)
Hayes, James Roger
Issue Date
1981
Department of Study
Physiology and Biophysics
Discipline
Physiology
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Biology, Animal Physiology
Language
eng
Abstract
Recent studies demonstrate that a number of the triarylethylene-type antiestrogens act as pro-drugs, being converted in vivo to metabolites having greater estrogenic and antiestrogenic potency than their parent compounds. This laboratory has revealed that two potent nonsteroidal antiestrogens,
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