Constructing a Numerical Phantom for MRSI Applications
Koksal, Okan
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https://hdl.handle.net/2142/55328
Description
Title
Constructing a Numerical Phantom for MRSI Applications
Author(s)
Koksal, Okan
Contributor(s)
Liang, Zhi-Pei
Issue Date
2014-05
Keyword(s)
MRSI
numerical
phantom
registration
interpolation
chemical shift
metabolite spectrum
Abstract
A phantom in the context of MRI is a tool that enables to test the performance of the imaging scheme. Magnetic resonance spectroscopic imaging (MRSI) is no exception to this. Therefore, the construction of an MRSI phantom enables the assessment of different imaging schemes as well as evaluating the imaging performance. In constructing an MRSI phantom, mapping parameters such as T1, T2, B inhomogeneity is important. Another important aspect of the MRSI phantom is the simulated frequency spectrum. A scheme is devised to generate a combined metabolite signal from each voxel using QM simulation data along with the aforementioned map parameters. To also generate realistic water and fat signals, in-vivo water and fat signals are registered onto the phantom image. The obtained spatial density image is then fed to a k-space imaging model, which will eventually allow rapid testing of different imaging modalities.
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