University of Illinois Urbana-Champaign

Surface Enhanced Raman Spectroscopy: A Computational Model and Measurements of Drugs

Tang, Tiantian

This item is only available for download by members of the University of Illinois community. Students, faculty, and staff at the U of I may log in with your NetID and password to view the item. If you are trying to access an Illinois-restricted dissertation or thesis, you can request a copy through your library's Inter-Library Loan office or purchase a copy directly from ProQuest.

Permalink

https://hdl.handle.net/2142/46469

Description

Title
Surface Enhanced Raman Spectroscopy: A Computational Model and Measurements of Drugs
Author(s)
Tang, Tiantian
Contributor(s)
Cunningham, Brian
Issue Date
2012-12
Keyword(s)
  • spectroscopy
  • Raman spectroscopy
  • Raman scattering
  • surface-enhanced Raman spectroscopy
  • label-free detection
  • biodetection
  • drug detection
  • device modeling
Abstract
Surface Enhanced Raman Spectroscopy (SERS) is a label-free detection method that provides fingerprints of molecules adsorbed on surface through their unique scattering modes. Plasmonic Nanodome Array (PNA) substrates for SERS are fabricated in our lab for detecting drug solutions in low concentrations. Because of the complex nature of PNA substrates, optics, and molecule adsorption, a computational model is needed for understanding and improving system performance. We developed this model by simulation, theoretical derivation, and experimental confirmation. In addition, various drugs in low concentration were measured and their Raman cross sections were calculated by the model.
Type of Resource
text
Language
en
Permalink
http://hdl.handle.net/2142/46469

Owning Collections

Senior Theses - Electrical and Computer Engineering PRIMARY
The best of ECE undergraduate research