UV light inactivation of adenovirus, coxsackievirus and murine norovirus
Vazquez Bravo, Bernardo
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https://hdl.handle.net/2142/29534
Description
Title
UV light inactivation of adenovirus, coxsackievirus and murine norovirus
Author(s)
Vazquez Bravo, Bernardo
Issue Date
2012-02-01T00:54:22Z
Director of Research (if dissertation) or Advisor (if thesis)
Mariñas, Benito J.
Department of Study
Civil & Environmental Eng
Discipline
Environ Engr in Civil Engr
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
M.S.
Degree Level
Thesis
Keyword(s)
Inactivation kinetics
Coxsackievirus
Murine Norovirus
Adenovirus
Abstract
The overall objective of this research project is to evaluate the efficiency of low-pressure (LP) and medium-pressure (MP) UV light irradiation to inactivate waterborne pathogens that are an increasing concern in drinking water. The inactivation of pathogens depends directly on the total UV dose or fluence (UV intensity multiplied by contact time) received by the microorganism. UV light irradiation is a treatment technology that relies on the inactivation of microorganisms by inducing genomic damage. However the results obtained in this research suggest that different wavelengths emitted by the medium-pressure UV source may be affecting not only the genome of the virus, but also proteins in the viral capsid that may disturb the ability of the virus to attach to the host cell and therefore its ability to complete its infection cycle. The conditions of the water used for the experimental work were modeled after those encountered at the Neuilly sur Marne water treatment plant in France.
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