Ultrasound tissue displacement and tissue elasticity imaging
Chen, Eric Chung Jay
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https://hdl.handle.net/2142/19171
Description
Title
Ultrasound tissue displacement and tissue elasticity imaging
Author(s)
Chen, Eric Chung Jay
Issue Date
1995
Doctoral Committee Chair(s)
O'Brien, William D.
Department of Study
Electrical and Computer Engineering
Discipline
Electrical Engineering
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Applied Mechanics
Engineering, Biomedical
Engineering, Electronics and Electrical
Health Sciences, Oncology
Language
eng
Abstract
In this dissertation, we investigate the feasibility of using high frequency ultrasound, to measure tissue motion and tissue elasticity for medical imaging applications. Ultrasound provides a means for non-invasive imaging of soft tissues, providing soft tissue contrast that cannot be achieved using conventional X-ray or tomographic imaging.
A two-dimensional correlation search algorithm is used to track local tissue displacements from radio frequency (RF) ultrasound echoes and from digitized ultrasound images. The accuracy of displacement imaging is investigated as a function of various imaging parameters such as ultrasound frequency and target size.
Ultrasound elasticity imaging consists of three basic steps: (1) measurement of tissue displacement, (2) estimation of tissue stresses and strains, and (3) recovery of tissue elasticity. Tissue strains and tissue elasticities are obtained from reconstructed tissue displacement fields and experimental measurements of applied stresses. Ultrasound elasticity measurements were compared with independent Instron load cell elasticity measurements.
Several examples of tissue displacement imaging of breast tumors in human breast cancer patients and ultrasound elasticity measurements of tissue phantoms (soft gels), and samples of bovine muscle and fat tissue are provided.
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