Director of Research (if dissertation) or Advisor (if thesis)
Beck, Carolyn L.
Department of Study
Industrial&Enterprise Sys Eng
Discipline
Systems & Entrepreneurial Engr
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
M.S.
Degree Level
Thesis
Date of Ingest
2011-01-14T22:51:38Z
Keyword(s)
Adaptive Control
Anesthesia
L1 Adaptive
Abstract
In this paper, we discuss the first application of recently developed L1-adaptive
control methods for the closed-loop control of anesthesia delivery during surgery.
Our initial objective, described herein, is to design controllers that are robust to
inter-patient variability, such that patients follow a prespecified Bispectral Index
(BIS) profile. The controllers are then evaluated on their ability to reject the
disturbances effects on the patients’ BIS trajectory that arise during the course
of surgery. The controllers are designed using identification-based models constructed
using clinical trial data. Two different L1-adaptive control schemes,
a state-feedback scheme and an output-feedback scheme, will be evaluated and
compared in terms of tracking performance, amount of anesthesia used, and robustness
to interpatient variability.
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